version: 2

# Règles biologiques (contradiction bio ⇒ ruled_out)
# ------------------------------------------------
# Ces règles permettent d'écarter un diagnostic (status: ruled_out) 
# si les preuves biologiques extraites le contredisent formellement.
# Elles génèrent aussi des alertes VETO-17 si la preuve est manquante.

missing_evidence:
  enabled: true
  veto: VETO-17
  severity: LOW
  score_penalty: 2

rules:
  # --- IONOGRAMME ---
  hyponatremia:
    enabled: true
    codes: ["E87.1"]
    analyte: sodium
    threshold_type: low
    message: "natrémie normale"

  hyperkalemia:
    enabled: true
    codes: ["E87.5"]
    analyte: potassium
    threshold_type: high
    message: "kaliémie normale"

  hypokalemia:
    enabled: true
    codes: ["E87.6"]
    analyte: potassium
    threshold_type: low
    message: "kaliémie normale"

  # --- HÉMATOLOGIE ---
  anemia:
    enabled: true
    codes: ["D50", "D50.0", "D50.1", "D50.8", "D50.9", "D51", "D52", "D53", "D55", "D56", "D57", "D58", "D59", "D60", "D61", "D62", "D63", "D64"]
    analyte: hemoglobin
    threshold_type: low
    message: "taux d'hémoglobine normal"

  thrombopenia:
    enabled: true
    codes: ["D69.4", "D69.5", "D69.6"]
    analyte: platelets
    threshold_type: low
    message: "taux de plaquettes normal"

  # --- RÉNAL ---
  acute_kidney_injury:
    enabled: true
    codes: ["N17", "N17.0", "N17.1", "N17.2", "N17.8", "N17.9", "N19"]
    analyte: creatinine
    threshold_type: high
    message: "créatininémie normale"

  # --- MÉTABOLISME ---
  hypoglycemia:
    enabled: true
    codes: ["E16.0", "E16.1", "E16.2"]
    analyte: glucose
    threshold_type: low
    message: "glycémie normale"

  diabetes_uncontrolled:
    enabled: true
    codes: ["E10.1", "E11.1"] # Avec complications aiguës (acidocétose, etc.)
    analyte: hba1c
    threshold_type: high
    threshold_value: 9.0
    message: "HbA1c < 9% (diabète non considéré comme déséquilibré selon HbA1c)"

  # --- THYROÏDE ---
  hypothyroidism:
    enabled: true
    codes: ["E02", "E03", "E03.0", "E03.1", "E03.2", "E03.8", "E03.9"]
    analyte: tsh
    threshold_type: high # TSH élevée = Hypo
    message: "TSH normale ou basse"

  hyperthyroidism:
    enabled: true
    codes: ["E05", "E05.0", "E05.1", "E05.2", "E05.8", "E05.9"]
    analyte: tsh
    threshold_type: low # TSH basse = Hyper
    message: "TSH normale ou élevée"